The only real difference between what you've flown on the Mooney is the engine instrument strip on the MFD of the G1000 Baron. You have two engines to monitor, so the system for displaying the information is a bit different. It's highly intuitive, though.
It's fun to fail items on individual engines and watch the G1000 bring it to your attention. G1000 or not, the 3D virtual cockpit is outstanding for the Baron. If you have the system resources to display it, we highly recommend doing takeoffs and pattern work in the 3D cockpit. You might still want to show the instruments only for landing, though.
Ref.: West, Jeff Van. Microsoft Flight Simulator X For Pilots: Real World Training. Wiley. Kindle Edition(Location 11917).